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Table of Contents
Year : 2021  |  Volume : 4  |  Issue : 3  |  Page : 563-564

Willingness and hesitancy toward COVID-19 vaccination among patients with cancer

Department of Nursing, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India

Date of Submission15-Jul-2021
Date of Decision30-Jul-2021
Date of Acceptance31-Jul-2021
Date of Web Publication08-Oct-2021

Correspondence Address:
Jaison Jacob
All India Institute of Medical Sciences, Bhubaneswar, Odisha
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/crst.crst_161_21

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How to cite this article:
Jacob J, Radhakrishnan RV, Issac A. Willingness and hesitancy toward COVID-19 vaccination among patients with cancer. Cancer Res Stat Treat 2021;4:563-4

How to cite this URL:
Jacob J, Radhakrishnan RV, Issac A. Willingness and hesitancy toward COVID-19 vaccination among patients with cancer. Cancer Res Stat Treat [serial online] 2021 [cited 2022 May 28];4:563-4. Available from: https://www.crstonline.com/text.asp?2021/4/3/563/327765

We read with interest the article, “COVID-19 vaccine uptake and vaccine hesitancy in Indian patients with cancer: A questionnaire-based survey,” authored by Noronha et al. in the recent issue of Cancer Research, Statistics, and Treatment.[1] The maiden efforts of the authors to landscape the concerns of patients with cancer and bring forth strategies to address their concerns are laudable. However, we would like to point out a few concerns with regard to interpreting the study results.

To start with, the study included only those patients with cancer who were aged above 45 years despite the prioritized availability of the COVID-19 vaccination for all the adults aged 18 years and above with terminal illness in the country from May 1, 2021. The delimitation of the study to patients with cancer aged above 45 years could have hindered the bringing forth of the views of the adolescent patients toward vaccine hesitancy. Furthermore, unlike in previous studies, the authors did not explore the reasons for willingness or acceptance of COVID-19 vaccination among those who received it. This could have helped in bringing out the determinants of willingness along with the reasons for hesitancy and provided a comprehensive understanding of the issue of concern.[2],[3] In the multivariate analysis, the factors considered for predicting the vaccine hesitancy were limited only to the sociodemographic variables, and important clinical variables specific to cancer were not included. Illness-specific factors, such as the clinical status, role of the participant in the family, other comorbidities, should have been considered in the multivariate analysis for predictors of vaccine hesitancy. Finally, the authors have not taken into account the important factors, such as trust in the government authority or belief about in need for vaccination, while analyzing the contributing factors or predictors of vaccine hesitancy among their subjects; these factors have been identified to be significant predictors of vaccine hesitancy among the public in many nations, including India.[2],[3] Notably, factors such as recommendation of the treating physician and proportion of vaccinated individuals in the close family could also significantly influence the intention for COVID-19 vaccination among patients with cancer.[4]

It is well established that patients with cancer are at a higher risk of complications and mortality from COVID-19 infection compared to the general population.[5] Therefore, prioritized vaccination has already been recommended for this subgroup by many expert guidelines.[6] Hence, precise documentation of vaccine hesitancy and its reasons are paramount to design and implement targeted educational interventions and prioritization measures to augment the COVID-19 vaccine uptake among patients with cancer.

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Conflicts of interest

There are no conflicts of interest.

  References Top

Noronha V, Abraham G, Bondili SK, Rajpurohit A, Menon RP, Gattani S, et al. COVID-19 vaccine uptake and vaccine hesitancy in Indian patients with cancer: A questionnaire-based survey. Cancer Res Stat Treat 2021;4:211-8.  Back to cited text no. 1
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Villarreal-Garza C, Vaca-Cartagena BF, Becerril-Gaitan A, Ferrigno AS, Mesa-Chavez F, Platas A, et al. Attitudes and factors associated with COVID-19 vaccine hesitancy among patients with breast cancer. JAMA Oncol 2021;7:12421244. [doi: 10.1001/jamaoncol.2021.1962].  Back to cited text no. 2
Jacob J, Stephen S, Issac A, Krishnan N, Vadakkethil Radhakrishnan R, R VV, et al. Determinants of willingness for COVID-19 vaccine: Implications for enhancing the proportion of vaccination among Indians. Cureus 2021;13:e15271.  Back to cited text no. 3
Kelkar AH, Blake JA, Cherabuddi K, Cornett H, McKee BL, Cogle CR. Vaccine enthusiasm and hesitancy in cancer patients and the impact of a webinar. Healthcare (Basel) 2021;9:351.  Back to cited text no. 4
Bansal N, Ghafur A. COVID-19 in oncology settings. Cancer Res Stat Treat 2020;3 Suppl S1:13-4.  Back to cited text no. 5
Desai A, Gainor JF, Hegde A, Schram AM, Curigliano G, Pal S, et al. COVID-19 vaccine guidance for patients with cancer participating in oncology clinical trials. Nat Rev Clin Oncol 2021;18:313-9.  Back to cited text no. 6


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