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STATISTICAL RESOURCE
Year : 2021  |  Volume : 4  |  Issue : 2  |  Page : 394-397

Basics of statistics - 5: Sample size calculation (iii): A narrative review for the use of computer software, tables, and online calculators


Department of Medical Oncology and Hemato-Oncology, Command Hospital Air Force, Bengaluru, Karnataka, India

Correspondence Address:
H S Darling
Department of Medical Oncology and Hemato-Oncology, Command Hospital Air Force, Bengaluru - 560 007, Karnataka, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/crst.crst_88_21

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Sample size calculation is essential for every analytical study aiming to obtain evidence-based results. This review describes the basics of the use of computer software for sample size calculation with the help of a few simple hypothetical examples. Published studies reporting on sample size calculation were identified from the PubMed and MEDLINE databases. In addition, relevant books were reviewed. Of the 125 articles identified from the database search, five articles fulfilling the eligibility criteria were included in this narrative review. This article describes the appropriate sample size calculation approach to be used in different scenarios using examples mimicking real-world clinical situations. In addition, each example describes an alternate method for sample size calculation to verify the result for ease of understanding. This will enable the confirmation of the accuracy of the calculated sample size to avoid incorrect estimation. Overall, the use of computer software, tables, and online calculators makes sample size calculation convenient, accurate, flexible, and easily reproducible.


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