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Year : 2020  |  Volume : 3  |  Issue : 2  |  Page : 327

Authors' reply to Krishnamurthy, Bhosale et al., and Mohan et al.

Department of Medical Oncology, Tata Memorial Centre, HBNI, Mumbai, Maharashtra, India

Date of Submission13-May-2020
Date of Decision14-May-2020
Date of Acceptance22-May-2020
Date of Web Publication19-Jun-2020

Correspondence Address:
Kumar Prabhash
Department of Medical Oncology, Tata Memorial Centre, HBNI, Mumbai - 400 012, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/CRST.CRST_194_20

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How to cite this article:
Patil V, Prabhash K. Authors' reply to Krishnamurthy, Bhosale et al., and Mohan et al. Cancer Res Stat Treat 2020;3:327

How to cite this URL:
Patil V, Prabhash K. Authors' reply to Krishnamurthy, Bhosale et al., and Mohan et al. Cancer Res Stat Treat [serial online] 2020 [cited 2021 Feb 24];3:327. Available from: https://www.crstonline.com/text.asp?2020/3/2/327/287238

We thank Krishnamurthy,[1] Bhosale et al.,[2] and Mohan et al.[3] for taking a keen interest in our work.[4],[5] We agree with the comments and points raised by all the authors. Indeed, tweaking of guidelines is required in desperate times as evidence is hard to come by. We would be fortunate if the coronavirus disease pandemic ends by the time the evidence is gathered.

We agree with Mohan et al. that strategies for the management of patients with unknown primary tumors with cervical node metastasis were not discussed, and we will try to address this issue in a separate manuscript. The management of Epstein-Barr virus-positive nasopharyngeal cancer is at present similar to that of any other nasopharyngeal cancer.[5] The human papillomavirus (HPV)-positive oropharyngeal cancers, though on the rise and comprising the majority of patients in the Western setting, are a rare entity in India.[6],[7] The impact of HPV in patients with a long history of smoking is negligible. Hence, we did not address it separately. Further, currently apart from staging in the 8th edition, the management of oropharyngeal cancers is similar, irrespective of the HPV status.[6],[8]

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Conflicts of interest

There are no conflicts of interest.

  References Top

Krishnamurthy A. Head-and-neck cancer management in the COVID-19 era: Practice recommendations. Cancer Res Stat Treat 2020;3:323-4.  Back to cited text no. 1
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Bhosale B, Katna R, Kalyani N. Adaptive approach toward the management of head-and-neck cancers during the COVID-19 crisis. Cancer Res Stat Treat 2020;3:324-5.  Back to cited text no. 2
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Mohan T, Nambiar K. Maintaining a sense of optimism - Carl Rogers. Cancer Res Stat Treat 2020;3:325-6.  Back to cited text no. 3
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Patil VM, Srikanth A, Noronha V, Joshi A, Dhumal S, Menon N, et al. The pattern of care in head-and-neck cancer: Comparison between before and during the COVID-19 pandemic. Cancer Res Stat Treat 2020;3 Suppl S1:7-12.  Back to cited text no. 4
Patil V, Noronha V, Chaturvedi P, Talapatra K, Joshi A, Menon N, et al. COVID-19 and head and neck cancer treatment. Cancer Res Stat Treat 2020;3 Suppl S1:15-28.  Back to cited text no. 5
Murthy V, Calcuttawala A, Chadha K, d'Cruz A, Krishnamurthy A, Mallick I, et al. Human papillomavirus in head and neck cancer in India: Current status and consensus recommendations. South Asian J Cancer 2017;6:93-8.  Back to cited text no. 6
[PUBMED]  [Full text]  
Patil VM, Noronha V, Joshi A, Agarwal J, Ghosh-Laskar S, Budrukkar A, et al. A randomized phase 3 trial comparing nimotuzumab plus cisplatin chemoradiotherapy versus cisplatin chemoradiotherapy alone in locally advanced head and neck cancer. Cancer 2019;125:3184-97.  Back to cited text no. 7
Noronha V, Patil VM, Joshi A, Mahimkar M, Patel U, Pandey MK, et al. Nimotuzumab-cisplatin-radiation versus cisplatin-radiation in HPV negative oropharyngeal cancer. Oncotarget 2020;11:399-408.  Back to cited text no. 8


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