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Table of Contents
LETTER TO EDITOR
Year : 2019  |  Volume : 2  |  Issue : 2  |  Page : 246-247

Clinical perspective in the management and outcomes of intraventricular tumors


Department of Surgical Oncology, Tata Memorial Hospital; Homi Bhabha National Institute (HBNI), Mumbai, Maharashtra, India

Date of Web Publication20-Dec-2019

Correspondence Address:
Saneya Pandrowala
Department of Surgical Oncology, 812, Golden Jubilee Block, Tata Memorial Hospital, Parel, Mumbai - 400 012, Maharashtra; Homi Bhabha National Institute (HBNI), Mumbai, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/CRST.CRST_67_19

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How to cite this article:
Pandrowala S. Clinical perspective in the management and outcomes of intraventricular tumors. Cancer Res Stat Treat 2019;2:246-7

How to cite this URL:
Pandrowala S. Clinical perspective in the management and outcomes of intraventricular tumors. Cancer Res Stat Treat [serial online] 2019 [cited 2020 Feb 26];2:246-7. Available from: http://www.crstonline.com/text.asp?2019/2/2/246/273682



The article by Kirankumar et al.[1] on 134 patients of intraventricular tumors gives us a review of a rare and challenging tumor with surgical options available for treatment and their complications. It gives a good detail about clinical profile of intraventricular tumors presenting at a tertiary care center and also the pathology. They have shown similar epidemiology in conjunction with available literature,[2] with the most commonly encountered truly intraventricular tumors being colloid cyst, subependymoma, ependymoma, neurocytoma, choroid plexus tumors, and subependymal giant cell astrocytomas. Other periventricular tumors growing into the ventricles have also been included.

They preferred the open approach in lateral and anterior third ventricle tumors with higher gross total and near-total excision rates than posterior third ventricle.[1] Almost 60% of the patients underwent endoscopic third ventriculostomy in those planned for endoscopic biopsy avoiding major open surgery, permanent shunt procedures (88%) for hydrocephalus patients, and other associated risks. They did not have any perioperative mortality or major morbidity; on follow-up, five patients had died with maximum patients being high-grade astrocytoma.

Although this review substantially contributes to the understanding of intraventricular tumors, we feel that the interpretation of the presented data does not give an idea as to which surgical modality was preferred based on the criteria chosen by the authors. The article mentions that 116 patients were operated by open microsurgical approach and 27 patients with endoscopic approach with some patients undergoing more than one surgery, but no details were mentioned for the same. The surgical approach used was mentioned as either of the two, but this would lead to a total of 143 patients whereas the analysis is with 134 patients.

As was also pointed out in the editorial,[3] 37 patients were given radiotherapy, and this was not discussed in detail regarding pathology and surgical excision. No details have been provided on molecular confirmation of histology or any chemotherapy used as adjuvant. The follow-up and survival data have also been given only as mean with no range or distinction between the surgical approaches used. The graph of cumulative survival gives a significant difference among the pathologically different groups of tumors, which is well known but does not tell us the difference in survival between the two surgical modalities.

These tumors are rare, and this article presents data on a large number of patients and definitely contributes to literature; however, finer details are not available and hence do not give an idea over and above the existing one, stating that open microsurgical or endoscopic procedures can be used for intraventricular tumors.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Kriankumar CK, Deshpande RP, Chandrasekhar YB, Rao IS, Panigrahi M, Babu PP. Clinical management and prognostic outcome of intracranial ventricular tumors: A study of 134 cases. Cancer Res Stat Treat 2019;2:10-5.  Back to cited text no. 1
  [Full text]  
2.
Agarwal A, Kanekar S. Intraventricular tumors. Semin Ultrasound CT MR 2016;37:150-8.  Back to cited text no. 2
    
3.
Krishnatry R. Challenges in the management of intraventricular tumors in the current era. Cancer Res Stat Treat 2019;2:72-3.  Back to cited text no. 3
  [Full text]  



This article has been cited by
1 Authorsę reply to: Pandrowala and Shaikh et al.
CK Kirankumar,RavindraPramod Deshpande,YB. V. K. Chandrasekhar,Manas Panigrahi,PhanithiPrakash Babu
Cancer Research, Statistics, and Treatment. 2019; 2(2): 247
[Pubmed] | [DOI]



 

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